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Ironwood Pharmaceuticals vs Xeris Biopharma Holdings

Ironwood Pharmaceuticals and Xeris Biopharma Holdings are similar in size: $296m and $292m of revenue in their latest fiscal years. Xeris Biopharma Holdings grew faster (43.7% against -15.7%). Ironwood Pharmaceuticals kept more of each dollar of sales as profit: a net margin of 8.1% against 0.2%.

Latest fiscal yearIronwood PharmaceuticalsIRWD, 2025Xeris Biopharma HoldingsXERS, 2025
Revenue $296m $292m
Revenue growth -15.7% 43.7%
Net income $24.0m $554,000
Operating margin 33.3% 8.5%
Net margin 8.1% 0.2%
Return on equity — —
Free cash flow $127m $28.6m
Cash $215m $111m
Total debt $585m $234m
Debt to equity — 1706.3%
Dividend per share — —
Dividend yield — —
Share buybacks — —
Employees 100 435
Market value $582m $1.81bn
Price vs our value range Below our value range —
Moat score 31 (Weak) 15 (Weak)
Insider trades, 12 months 0 buys, 18 sales 0 buys, 33 sales

Each figure is from the company's latest annual report and links to the page it comes from. Fiscal years can end on different dates. Market value and the value verdict use the delayed price shown on the stock pages. Not a recommendation.

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Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.