undamentalytics Newsletter

Pharmaceuticals stocks

86 US-listed companies in pharmaceuticals, with $591.9bn of combined revenue in their latest fiscal years. Johnson & Johnson is the largest ($94.2bn). The fastest grower with at least $100m of revenue in both years is Travere Therapeutics, Inc., up 110.5%. The median company grew 7.5% with a net margin of 7.1%.

Companies86
Combined revenue$591.9bn
Median revenue growth7.5%
Median net margin7.1%
Median return on equity10.4%
#CompanyRevenueGrowthNet marginROEFiscal year
1 Johnson & JohnsonJNJ $94.2bn 6.0% 28.5% 35.0% 2025
2 Lilly (Eli)LLY $65.2bn 44.7% 31.7% 101.2% 2025
3 Merck & Co.MRK $65.0bn 1.3% 28.1% 36.9% 2025
4 PfizerPFE $62.6bn −1.6% 12.4% 8.9% 2025
5 Astrazeneca PLCAZN $58.7bn 8.6% 17.4% 22.9% 2025
6 Bristol Myers SquibbBMY $48.2bn −0.2% 14.6% 40.5% 2025
7 Novo Nordisk A SNVO $46.8bn 11.1% 33.1% 61.6% 2025
8 GSK plcGSK $43.1bn 7.5% 17.5% 38.5% 2025
9 Universe Pharmaceuticals IncUPC $17.9bn −22.4% −20.6% −7.2% 2025
10 Haleon plcHLN $14.6bn 1.3% 15.1% 10.4% 2025
11 ViatrisVTRS $14.3bn −3.0% −24.6% −21.1% 2025
12 Bausch Health Companies Inc.BHC $10.3bn 6.7% 1.5% — 2025
13 ZoetisZTS $9.5bn 2.3% 28.2% 65.3% 2025
14 Organon & Co.OGN $6.2bn −2.9% 3.0% 30.6% 2025
15 Elanco Animal Health IncELAN $4.7bn 6.2% −4.9% −3.7% 2025
16 Jazz Pharmaceuticals plcJAZZ $4.3bn 4.9% −8.3% −8.5% 2025
17 Amneal Pharmaceuticals, Inc.AMRX $3.0bn 8.0% 2.4% — 2025
18 Royalty Pharma plcRPRX $2.4bn 5.1% 32.4% 7.7% 2025
19 Lantheus Holdings, Inc.LNTH $1.5bn 0.5% 15.2% 21.4% 2025
20 Phibro Animal Health CorpPAHC $1.5bn 17.1% 6.6% 29.7% 2026
21 Indivior Pharmaceuticals, Inc.INDV $1.2bn 4.3% 16.9% — 2025
22 Nasus Pharma LtdNSRX $1.2bn — −0.5% — 2025
23 Trulieve Cannabis Corp.TRLV $1.2bn −0.4% −9.9% −9.7% 2025
24 Prestige Consumer Healthcare Inc.PBH $1.1bn −4.3% 17.5% 10.2% 2026
25 ANI Pharmaceuticals IncANIP $883m 43.8% 8.9% 16.6% 2025
26 Harmony Biosciences Holdings, Inc.HRMY $868m 21.5% 18.3% 20.8% 2025
27 Collegium Pharmaceutical, IncCOLL $781m 23.6% 8.1% 23.7% 2025
28 Corcept Therapeutics IncCORT $761m 12.8% 13.1% 15.0% 2025
29 Emergent Biosolutions Inc.EBS $743m −28.8% 7.1% 10.5% 2025
30 Pacira Biosciences, Inc.PCRX $726m 3.6% 1.0% 1.0% 2025
31 Amphastar Pharmaceuticals, Inc.AMPH $720m −1.7% 13.6% 12.9% 2025
32 Supernus Pharmaceuticals, Inc.SUPN $719m 8.6% −5.4% −3.7% 2025
33 Axsome Therapeutics, Inc.AXSM $638m 65.5% −28.7% — 2025
34 Opko Health, Inc.OPK $607m −14.9% −37.2% −17.1% 2025
35 AlvotechALVO $586m 19.7% 4.8% — 2025
36 Travere Therapeutics, Inc.TVTX $491m 110.5% −5.2% −29.4% 2025
37 Innoviva, Inc.INVA $411m 14.7% 65.9% 29.1% 2025
38 Evolus, Inc.EOLS $297m 11.6% −17.4% — 2025
39 Ironwood Pharmaceuticals IncIRWD $296m −15.7% 8.1% — 2025
40 Rigel Pharmaceuticals IncRIGL $294m 64.1% 124.7% 185.9% 2025
41 Xeris Biopharma Holdings, Inc.XERS $292m 43.7% 0.2% — 2025
42 Harrow, Inc.HROW $272m 36.4% −1.9% −8.4% 2025
43 Aurora Cannabis IncACB $232m 11.7% −42.4% −25.9% 2026
44 Vanda Pharmaceuticals Inc.VNDA $216m 8.7% −102.0% −50.9% 2025
45 Amarin Corp plc\ukAMRN $214m −6.5% −18.2% −8.2% 2025
46 Biote Corp.BTMD $192m −2.5% 14.1% — 2025
47 Organigram Global Inc.OGI $185m 57.8% −9.6% −7.4% 2025
48 Kamada LTDKMDA $180m 12.1% 11.2% 7.6% 2025
49 Liquidia CorpLQDA $158m 1031.2% −43.5% −111.1% 2025
50 Heron Therapeutics, Inc.HRTX $155m 7.4% −13.0% — 2025
51 Cronos Group Inc.CRON $147m 24.6% −6.4% −0.9% 2025
52 Natural Alternatives International IncNAII $143m 9.7% −14.5% −35.0% 2026
53 Niagen Bioscience, Inc.NAGE $129m 29.9% 13.4% 28.3% 2025
54 Gyre Therapeutics, Inc.GYRE $117m 10.2% 8.5% 15.7% 2025
55 Zevra Therapeutics, Inc.ZVRA $106m 350.9% 78.2% 85.7% 2025
56 Eton Pharmaceuticals, Inc.ETON $80m 104.9% −5.8% −18.2% 2025
57 Rockwell Medical, Inc.RMTI $69m −31.8% −7.7% −15.3% 2025
58 Journey Medical CorpDERM $62m 10.2% −18.5% −44.0% 2025
59 Aytu Biopharma, IncAYTU $58m −13.3% −24.8% −52.6% 2026
60 Aquestive Therapeutics, Inc.AQST $45m −22.6% −188.1% — 2025
61 Cumberland Pharmaceuticals IncCPIX $45m 17.6% −6.4% −11.9% 2025
62 Biofrontera Inc.BFRI $42m 11.7% −25.3% −141.3% 2025
63 IM Cannabis Corp.IMCC $39m −0.7% −20.7% — 2025
64 BGM Group Ltd.BGM $38m 51.1% −52.6% −9.2% 2025
65 Sunshine Biopharma Inc.SBFM $36m 4.1% −16.5% −25.7% 2025
66 Verrica Pharmaceuticals Inc.VRCA $36m 370.2% −50.3% — 2025
67 Eyepoint, Inc.EYPT $31m −27.5% −739.4% −72.2% 2025
68 Scilex Holding CoSCLX $30m −46.5% −1236.4% — 2025
69 Sol-gel Technologies Ltd.SLGL $19m 68.0% −31.6% −23.7% 2025
70 Pelthos Therapeutics Inc.PTHS $17m — −257.9% — 2025
71 Zhengye Biotechnology Holding LtdZYBT $16m −37.5% −60.0% −26.0% 2025
72 Jaguar Health, Inc.JAGX $12m −1.5% −465.4% — 2025
73 China Pharma Holdings, Inc.CPHI $4m −8.5% −76.9% −20.9% 2025
74 Therapeuticsmd, Inc.TXMD $3m 71.6% −18.8% −2.1% 2025
75 Traws Pharma, Inc.TRAW $3m 1134.5% 328.7% — 2025
76 Nutriband Inc.NTRB $2m −4.8% −404.1% −125.6% 2026
77 Lipocine Inc.LPCN $2m −82.3% −487.1% −54.3% 2025
78 China SXT Pharmaceuticals, Inc.SXTC $1m −34.6% −545.2% −27.5% 2026
79 60 Degrees Pharmaceuticals, Inc.SXTP $1m 65.5% −732.5% −196.4% 2025
80 Scienture Holdings, Inc.SCNX $431,609 215.9% −9618.0% −55.6% 2025
81 Vyome Holdings, IncHIND $319,714 −96.0% −3209.7% — 2025
82 Akanda Corp.AKAN $258,075 −69.2% −467.1% — 2025
83 Gelteq LtdGELS $107,317 99.7% −4011.9% −37.7% 2025
84 Talphera, Inc.TLPH $28,000 — −51035.7% −114.2% 2025
85 PRF Technologies Ltd.PRFX $17,000 — −29541.2% −96.9% 2025
86 Aspire-lakewood Holdings, Inc.ASBP $6,202 — −394725.1% — 2025

Medians cover companies with at least $100m of revenue (growth: in both years). Growth is the latest fiscal year against the year before and includes acquisitions.

Other health care industries

Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.