undamentalytics Newsletter

Biggest R&D spenders in the US

Research and development expense in the latest fiscal year, as reported in the income statement. Alphabet Inc. (Class A) leads with $61.1bn in fiscal 2025. The top 100 of 1,913 companies with a figure on file.

#CompanySectorResearch and developmentFiscal year
1 Alphabet Inc. (Class A)GOOGL Communication Services $61.1bn 2025
2 Meta PlatformsMETA Communication Services $57.4bn 2025
3 Apple Inc.AAPL Technology $45.8bn 2026
4 Microsoft CorporationMSFT Technology $35.6bn 2026
5 NVIDIA CorporationNVDA Technology $18.5bn 2026
6 Merck & Co.MRK Health Care $15.8bn 2025
7 Johnson & JohnsonJNJ Health Care $14.7bn 2025
8 Astrazeneca PLCAZN Health Care $14.2bn 2025
9 IntelINTC Technology $13.8bn 2025
10 Lilly (Eli)LLY Health Care $13.3bn 2025
11 Stellantis N.V.STLA Consumer Discretionary $12.6bn 2025
12 BroadcomAVGO Technology $11.0bn 2025
13 PfizerPFE Health Care $10.4bn 2025
14 Toyota Motor Corp/TM Consumer Discretionary $10.4bn 2026
15 Oracle CorporationORCL Technology $10.3bn 2026
16 Honda Motor Co LTDHMC Consumer Discretionary $10.2bn 2026
17 Bristol Myers SquibbBMY Health Care $10.0bn 2025
18 GSK plcGSK Health Care $9.9bn 2025
19 CiscoCSCO Technology $9.6bn 2026
20 Ford Motor CompanyF Consumer Discretionary $9.4bn 2025
21 Alibaba Group Holding LtdBABA Consumer Discretionary $9.4bn 2026
22 AbbVieABBV Health Care $9.1bn 2025
23 QualcommQCOM Technology $9.0bn 2025
24 IBMIBM Technology $8.3bn 2025
25 Advanced Micro DevicesAMD Technology $8.1bn 2025
26 Taiwan Semiconductor Manufacturing Co LTDTSM Technology $7.9bn 2025
27 Novo Nordisk A SNVO Health Care $7.9bn 2025
28 SAP SESAP Technology $7.5bn 2025
29 AmgenAMGN Health Care $7.3bn 2025
30 Tesla, Inc.TSLA Consumer Discretionary $6.4bn 2025
31 SalesforceCRM Technology $6.0bn 2026
32 Regeneron PharmaceuticalsREGN Health Care $5.9bn 2025
33 Gilead SciencesGILD Health Care $5.8bn 2025
34 Micron TechnologyMU Technology $5.7bn 2026
35 Asml Holding NVASML Technology $5.3bn 2025
36 Ericsson LM Telephone CoERIC Technology $5.0bn 2025
37 Adobe Inc.ADBE Technology $4.3bn 2025
38 Vertex PharmaceuticalsVRTX Health Care $3.9bn 2025
39 BoeingBA Industrials $3.6bn 2025
40 Applied MaterialsAMAT Technology $3.6bn 2025
41 UberUBER Industrials $3.4bn 2025
42 NetflixNFLX Communication Services $3.4bn 2025
43 IntuitINTU Technology $3.4bn 2026
44 Atlassian CorpTEAM Technology $3.3bn 2026
45 Dell TechnologiesDELL Technology $3.1bn 2026
46 ModernaMRNA Health Care $3.1bn 2025
47 Jd.com, Inc.JD Consumer Discretionary $3.1bn 2025
48 ServiceNowNOW Technology $3.0bn 2025
49 Abbott LaboratoriesABT Health Care $2.9bn 2025
50 Block, Inc.XYZ Financials $2.9bn 2025
51 MedtronicMDT Health Care $2.9bn 2026
52 Baidu, Inc.BIDU Communication Services $2.8bn 2025
53 RTX CorporationRTX Industrials $2.8bn 2025
54 ARM Holdings PLCARM Technology $2.8bn 2026
55 Workday, Inc.WDAY Technology $2.7bn 2026
56 Palo Alto NetworksPANW Technology $2.6bn 2026
57 Hewlett Packard EnterpriseHPE Technology $2.5bn 2025
58 Synopsys IncSNPS Technology $2.5bn 2025
59 Netease, Inc.NTES Communication Services $2.5bn 2025
60 Biontech SEBNTX Health Care $2.4bn 2025
61 Lam ResearchLRCX Technology $2.4bn 2026
62 NXP SemiconductorsNXPI Technology $2.4bn 2025
63 AirbnbABNB Consumer Discretionary $2.4bn 2025
64 Deere & CompanyDE Industrials $2.3bn 2025
65 PDD Holdings Inc.PDD Consumer Discretionary $2.3bn 2025
66 Mercadolibre IncMELI Industrials $2.3bn 2025
67 Caterpillar Inc.CAT Industrials $2.1bn 2025
68 Trip.com Group LtdTCOM Consumer Discretionary $2.1bn 2025
69 Procter & GamblePG Consumer Staples $2.1bn 2026
70 Texas InstrumentsTXN Technology $2.1bn 2025
71 Marvell TechnologyMRVL Technology $2.1bn 2026
72 Boston ScientificBSX Health Care $2.1bn 2025
73 IncyteINCY Health Care $2.1bn 2025
74 Stmicroelectronics N.V.STM Technology $2.0bn 2025
75 Lockheed MartinLMT Industrials $2.0bn 2025
76 Snowflake Inc.SNOW Technology $2.0bn 2026
77 Koninklijke Philips NVPHG Health Care $1.9bn 2025
78 Honeywell TechnologiesHON Industrials $1.8bn 2025
79 Snap IncSNAP Communication Services $1.8bn 2025
80 BiogenBIIB Health Care $1.8bn 2025
81 Cadence Design Systems IncCDNS Technology $1.8bn 2025
82 Analog DevicesADI Technology $1.8bn 2025
83 CoinbaseCOIN Financials $1.7bn 2025
84 Rivian Automotive, Inc. / DERIVN Consumer Discretionary $1.7bn 2025
85 Autodesk, Inc.ADSK Technology $1.6bn 2026
86 eBay Inc.EBAY Consumer Discretionary $1.6bn 2025
87 Stryker CorporationSYK Health Care $1.6bn 2025
88 HP Inc.HPQ Technology $1.6bn 2025
89 Danaher CorporationDHR Health Care $1.6bn 2025
90 GE AerospaceGE Industrials $1.6bn 2025
91 Spotify Technology S.a.SPOT Communication Services $1.6bn 2025
92 Li Auto Inc.LI Consumer Discretionary $1.6bn 2025
93 Roblox CorpRBLX Communication Services $1.6bn 2025
94 Datadog, Inc.DDOG Technology $1.5bn 2025
95 Shopify Inc.SHOP Technology $1.5bn 2025
96 KLA CorporationKLAC Technology $1.5bn 2026
97 Sarepta Therapeutics, Inc.SRPT Health Care $1.5bn 2025
98 NIO Inc.NIO Consumer Discretionary $1.5bn 2025
99 Corteva, Inc.CTVA Materials $1.5bn 2025
100 DoorDashDASH Consumer Discretionary $1.4bn 2025

Would buying this list have paid?

Buying the top 100 companies by research and development, as the list stood each quarter since September 30, 2010, would have returned +20.1% a year against +14.6% for the S&P 500. It beat the index, but mostly by moving more than the market (beta 1.21); after allowing for that, the extra return could be chance.

$0$100k$200k 201020122014201620182020202220242026 $187k$88.5k
Top 100 by research and developmentS&P 500, buy and hold $10,000 invested in September 30, 2010, before costs. Strategy: equal amounts in the list's top 100, rebuilt every quarter from figures for quarters that ended at least 90 days earlier.
Return a yearTypical yearly swingSharpe ratioBiggest dropMoves with market (beta)
Top 100 by research and development+20.1%19.4%0.98-30.2%1.21
S&P 500, buy and hold+14.6%14.7%0.92-23.9%1.00
  • Ahead of the S&P 500 in 51.6% of 64 quarters.
  • Extra return after allowing for market risk (alpha): +2.8% a year No reliable evidence t = 1.30
  • Against the S&P 500: +5.7% a year in 2010–2017, +5.2% in 2018–2026.

A backtest describes the past under fixed rules; it is not a forecast. Today's companies only (firms that failed or were taken over are missing, which flatters the result), and fewer companies qualify in the early years; figures as later filed, including restatements; no trading costs; trailing twelve months stand in for the latest fiscal year. Sharpe ratio is return above the Treasury bill rate per unit of swing. All our backtests.

More rankings

Figures from each company's latest annual report filed with the SEC (10-K or 20-F), as reported, with the fiscal year shown. Not investment advice. How we read filings: methodology.